3G11

Structure of E. coli FabF(C163Q) in complex with dihydrophenyl platensimycin

Summary for 3G11

Entry DOI	10.2210/pdb3g11/pdb
Related	2GFX 3G0Y
Descriptor	3-oxoacyl-[acyl-carrier-protein] synthase 2, 3-({3-[(1S,4S,4aS,6S,7S,9S,9aR)-1,6-dimethyl-2-oxo-4-phenyldecahydro-6,9-epoxy-4a,7-methanobenzo[7]annulen-1-yl]propanoyl}amino)-2,4-dihydroxybenzoic acid (3 entities in total)
Functional Keywords	ketoacyl synthase, platensimycin, acyltransferase, fatty acid biosynthesis, lipid synthesis, transferase
Biological source	Escherichia coli
Total number of polymer chains	1
Total formula weight	45181.88
Authors	Soisson, S.M.,Parthasarathy, G. (deposition date: 2009-01-29, release date: 2009-03-17, Last modification date: 2023-09-06)
Primary citation	Shen, H.C.,Ding, F.X.,Singh, S.B.,Parthasarathy, G.,Soisson, S.M.,Ha, S.N.,Chen, X.,Kodali, S.,Wang, J.,Dorso, K.,Tata, J.R.,Hammond, M.L.,Maccoss, M.,Colletti, S.L. Synthesis and biological evaluation of platensimycin analogs. Bioorg.Med.Chem.Lett., 19:1623-1627, 2009 Cited by PubMed: 19233644 DOI: 10.1016/j.bmcl.2009.02.006 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation