3G11

Structure of E. coli FabF(C163Q) in complex with dihydrophenyl platensimycin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	3-oxoacyl-[acyl-carrier-protein] synthase 2	polymer	427	44662.3	1	UniProt (P0AAI5) Pfam (PF00109) Pfam (PF02801)	Escherichia coli	3-oxoacyl-[acyl-carrier-protein] synthase II, Beta-ketoacyl-ACP synthase II, KAS II
2	B (A)	3-({3-[(1S,4S,4aS,6S,7S,9S,9aR)-1,6-dimethyl-2-oxo-4-phenyldecahydro-6,9-epoxy-4a,7-methanobenzo[7]annulen-1-yl]propanoyl}amino)-2,4-dihydroxybenzoic acid	non-polymer		519.6	1	Chemie (P9C)
3	C (A)	water	water		18.0	404	Chemie (HOH)

Sequence modifications

A: 1 - 412 (UniProt: P0AAI5)

PDB	External Database	Details
Met -14	-	expression tag
Arg -13	-	expression tag
Gly -12	-	expression tag
Ser -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
Gly -4	-	expression tag
Ser -3	-	expression tag
Ala -2	-	expression tag
Cys -1	-	expression tag
Val 0	-	expression tag
Gln 163	Cys 164	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	44662.3
Non-Polymers*	Number of molecules	1
	Total formula weight	519.6
All*	Total formula weight	45181.9

*Water molecules are not included.