3FY2

Human EphA3 Kinase and Juxtamembrane Region Bound to Substrate KQWDNYEFIW

3FY2 の概要

• エントリーDOI: 10.2210/pdb3fy2/pdb
• 関連するPDBエントリー: 1IR3 2GSF 2QOC 3FXX
• 分子名称: Ephrin type-A receptor 3, peptide substrate (3 entities in total)
• 機能のキーワード: receptor tyrosine kinase, juxtamembrane segment, structural genomics, peptide co-crystal structure, structural genomics consortium, sgc, atp-binding, cell membrane, glycoprotein, kinase, membrane, nucleotide-binding, phosphoprotein, receptor, secreted, transferase, transmembrane, tyrosine-protein kinase
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Isoform 1: Cell membrane ; Single-pass type I membrane protein . Isoform 2: Secreted : P29320
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 43249.28

構造登録者

Davis, T.,Walker, J.R.,Mackenzie, F.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Dhe-Paganon, S.,Structural Genomics Consortium (SGC) (登録日: 2009-01-21, 公開日: 2009-02-03, 最終更新日: 2023-09-06)

• 主引用文献: Davis, T.L.,Walker, J.R.,Allali-Hassani, A.,Parker, S.A.,Turk, B.E.,Dhe-Paganon, S.; Structural recognition of an optimized substrate for the ephrin family of receptor tyrosine kinases.; Febs J., 276:4395-4404, 2009; PubMed: 19678838; DOI: 10.1111/j.1742-4658.2009.07147.x

実験手法

X-RAY DIFFRACTION (1.8 Å)