3FWO

The large ribosomal subunit from Deinococcus radiodurans complexed with Methymycin

3FWO の概要

• エントリーDOI: 10.2210/pdb3fwo/pdb
• 関連するPDBエントリー: 1NKW
• 分子名称: 23S RIBOSOMAL RNA, 5S RIBOSOMAL RNA, (3R,4S,5S,7R,9E,11S,12R)-12-ethyl-11-hydroxy-3,5,7,11-tetramethyl-2,8-dioxooxacyclododec-9-en-4-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside (3 entities in total)
• 機能のキーワード: ribosome; large subunit; 50s; deinococcus radiodurans; x-ray structure; peptidyl-transferase, peptide bond formation, antibiotics, macrolides, ribosome
• 由来する生物種: Deinococcus radiodurans R1; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 971904.39

構造登録者

Auerbach, T.,Mermershtain, I.,Bashan, A.,Davidovich, C.,Rozenberg, H.,Sherman, D.H.,Yonath, A. (登録日: 2009-01-19, 公開日: 2010-01-19, 最終更新日: 2024-02-21)

• 主引用文献: Auerbach, T.,Mermershtain, I.,Bashan, A.,Davidovich, C.,Rozenberg, H.,Sherman, D.H.,Yonath, A.; Structural basis for the antibacterial activity of the 12-membered-ring mono-sugar macrolide methymycin; Biotechnologia, 1:24-35, 2009

実験手法

X-RAY DIFFRACTION (3.71 Å)