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3FUR

Crystal Structure of PPARg in complex with INT131

Summary for 3FUR
Entry DOI10.2210/pdb3fur/pdb
DescriptorPeroxisome proliferator-activated receptor gamma, Nuclear receptor coactivator 1, 2,4-dichloro-N-[3,5-dichloro-4-(quinolin-3-yloxy)phenyl]benzenesulfonamide, ... (5 entities in total)
Functional Keywordsnuclear receptor, ppargamma, partial agonist, activator, alternative splicing, diabetes mellitus, disease mutation, dna-binding, metal-binding, nucleus, obesity, phosphoprotein, polymorphism, receptor, transcription, transcription regulation, zinc, zinc-finger, int131, transcription-transcription regulator complex, transcription/transcription regulator
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains2
Total formula weight32987.36
Authors
Wang, Z.,Liu, J.,Walker, N. (deposition date: 2009-01-14, release date: 2009-06-09, Last modification date: 2024-03-20)
Primary citationMotani, A.,Wang, Z.,Weiszmann, J.,McGee, L.R.,Lee, G.,Liu, Q.,Staunton, J.,Fang, Z.,Fuentes, H.,Lindstrom, M.,Liu, J.,Biermann, D.H.,Jaen, J.,Walker, N.P.,Learned, R.M.,Chen, J.L.,Li, Y.
INT131: a selective modulator of PPAR gamma.
J.Mol.Biol., 386:1301-1311, 2009
Cited by
PubMed: 19452630
DOI: 10.1016/j.jmb.2009.01.025
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

217705

數據於2024-03-27公開中

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