3FUR

Crystal Structure of PPARg in complex with INT131

3FUR の概要

• エントリーDOI: 10.2210/pdb3fur/pdb
• 分子名称: Peroxisome proliferator-activated receptor gamma, Nuclear receptor coactivator 1, 2,4-dichloro-N-[3,5-dichloro-4-(quinolin-3-yloxy)phenyl]benzenesulfonamide, ... (5 entities in total)
• 機能のキーワード: nuclear receptor, ppargamma, partial agonist, activator, alternative splicing, diabetes mellitus, disease mutation, dna-binding, metal-binding, nucleus, obesity, phosphoprotein, polymorphism, receptor, transcription, transcription regulation, zinc, zinc-finger, int131, transcription-transcription regulator complex, transcription/transcription regulator
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 32987.36

構造登録者

Wang, Z.,Liu, J.,Walker, N. (登録日: 2009-01-14, 公開日: 2009-06-09, 最終更新日: 2024-03-20)

• 主引用文献: Motani, A.,Wang, Z.,Weiszmann, J.,McGee, L.R.,Lee, G.,Liu, Q.,Staunton, J.,Fang, Z.,Fuentes, H.,Lindstrom, M.,Liu, J.,Biermann, D.H.,Jaen, J.,Walker, N.P.,Learned, R.M.,Chen, J.L.,Li, Y.; INT131: a selective modulator of PPAR gamma.; J.Mol.Biol., 386:1301-1311, 2009; PubMed: 19452630; DOI: 10.1016/j.jmb.2009.01.025

実験手法

X-RAY DIFFRACTION (2.3 Å)