3FMR

Crystal structure of an Encephalitozoon cuniculi methionine aminopeptidase type 2 with angiogenesis inhibitor TNP470 bound

「3D0D」から置き換えられました

3FMR の概要

• エントリーDOI: 10.2210/pdb3fmr/pdb
• 関連するPDBエントリー: 3FM3 3FMQ
• 分子名称: Methionine aminopeptidase 2, FE (III) ION, (1R,2S,3S,4R)-4-hydroxy-2-methoxy-4-methyl-3-[(2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]cyclohexyl (chloroacetyl)carbamate, ... (5 entities in total)
• 機能のキーワード: methionine aminopeptidase type2, metap2, metap2 tnp470 complex, encephalitozoon cuniculi, structural genomics, psi-2, protein structure initiative, new york sgx research center for structural genomics, nysgxrc, aminopeptidase, cobalt, hydrolase, metal-binding, protease
• 由来する生物種: Encephalitozoon cuniculi
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 81474.30

構造登録者

Alvarado, J.J.,Russell, M.,Zhang, A.,Adams, J.,Toro, R.,Burley, S.K.,Weiss, L.M.,Almo, S.C.,New York SGX Research Center for Structural Genomics (NYSGXRC) (登録日: 2008-12-22, 公開日: 2009-01-13, 最終更新日: 2023-09-06)

• 主引用文献: Alvarado, J.J.,Nemkal, A.,Sauder, J.M.,Russell, M.,Akiyoshi, D.E.,Shi, W.,Almo, S.C.,Weiss, L.M.; Structure of a microsporidian methionine aminopeptidase type 2 complexed with fumagillin and TNP-470.; Mol.Biochem.Parasitol., 168:158-167, 2009; PubMed: 19660503; DOI: 10.1016/j.molbiopara.2009.07.008

実験手法

X-RAY DIFFRACTION (2.89 Å)