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3FMR

Crystal structure of an Encephalitozoon cuniculi methionine aminopeptidase type 2 with angiogenesis inhibitor TNP470 bound

Replaces:  3D0D
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Methionine aminopeptidase 2polymer35840029.42UniProt (Q8SR45)
Pfam (PF00557)
Encephalitozoon cuniculiMetAP 2, MAP-2, Peptidase M 2
2C, D, I, J
(A, B)
FE (III) IONnon-polymer55.84Chemie (FE)
3E, K
(A, B)
(1R,2S,3S,4R)-4-hydroxy-2-methoxy-4-methyl-3-[(2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]cyclohexyl (chloroacetyl)carbamatenon-polymer403.92Chemie (TN4)
4F, G, H, L
(A, B)
SULFATE IONnon-polymer96.14Chemie (SO4)
5M, N
(A, B)
waterwater18.017Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight80058.9
Non-Polymers*Number of molecules10
Total formula weight1415.4
All*Total formula weight81474.3
*Water molecules are not included.

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PDB entries from 2025-12-03

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