3FMG

Structure of rotavirus outer capsid protein VP7 trimer in complex with a neutralizing Fab

Summary for 3FMG

Entry DOI	10.2210/pdb3fmg/pdb
Descriptor	Fab of neutralizing antibody 4F8, light chain, Fab of neutralizing antibody 4F8, heavy chain, Glycoprotein VP7, ... (4 entities in total)
Functional Keywords	antibody-antigen complex, calcium dependent trimer, antiparallel beta-sandwich, jelly roll, alpha-beta-alpha sandwich, rossmann fold, capsid protein, endoplasmic reticulum, glycoprotein, membrane, transmembrane, virion, immune system
Biological source	Simian rotavirus More
Cellular location	Virion (By similarity): P12476
Total number of polymer chains	3
Total formula weight	78281.81
Authors	Aoki, S.T.,Settembre, E.C.,Trask, S.D.,Greenberg, H.B.,Harrison, S.C.,Dormitzer, P.R. (deposition date: 2008-12-22, release date: 2009-06-23, Last modification date: 2023-09-06)
Primary citation	Aoki, S.T.,Settembre, E.C.,Trask, S.D.,Greenberg, H.B.,Harrison, S.C.,Dormitzer, P.R. Structure of rotavirus outer-layer protein VP7 bound with a neutralizing Fab. Science, 324:1444-1447, 2009 Cited by PubMed: 19520960 DOI: 10.1126/science.1170481 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.4 Å)

Structure validation