3FMG
Structure of rotavirus outer capsid protein VP7 trimer in complex with a neutralizing Fab
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0019028 | cellular_component | viral capsid |
| A | 0039621 | cellular_component | T=13 icosahedral viral capsid |
| A | 0039624 | cellular_component | viral outer capsid |
| A | 0044166 | cellular_component | host cell endoplasmic reticulum lumen |
| A | 0044423 | cellular_component | virion component |
| A | 0046813 | biological_process | receptor-mediated virion attachment to host cell |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 327 |
| Chain | Residue |
| A | GLN177 |
| A | LYS183 |
| A | ASP228 |
| A | VAL229 |
| A | ASP231 |
| A | ASP301 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A 328 |
| Chain | Residue |
| A | GLU216 |
| A | ASP95 |
| A | GLY206 |
| A | THR214 |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH |
| Chain | Residue | Details |
| L | TYR192-HIS198 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Region: {"description":"CNP motif; interaction with ITGAV/ITGB3","evidences":[{"source":"HAMAP-Rule","id":"MF_04131","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"15452204","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Region: {"description":"LVD motif; interaction with ITGA4/ITGB1 heterodimer","evidences":[{"source":"HAMAP-Rule","id":"MF_04131","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Region: {"description":"GPR motif; interaction with ITGAX/ITGB2","evidences":[{"source":"HAMAP-Rule","id":"MF_04131","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_04131","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"19520960","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_04131","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"19487668","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19520960","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
