3FME

Crystal Structure of Human Mitogen-Activated Protein Kinase Kinase 6 (MEK6) Activated Mutant (S207D, T211D)

3FME の概要

• エントリーDOI: 10.2210/pdb3fme/pdb
• 分子名称: Dual specificity mitogen-activated protein kinase kinase 6, STAUROSPORINE (3 entities in total)
• 機能のキーワード: kinase, active mutant, structural genomics consortium, scg, sgc, atp-binding, nucleotide-binding, phosphoprotein, serine/threonine-protein kinase, transferase, tyrosine-protein kinase
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Nucleus : P52564
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 33216.42

構造登録者

Filippakopoulos, P.,Barr, A.,Pike, A.C.W.,Berridge, G.,Elkins, J.,Fedorov, O.,Keates, T.,Savitsky, P.,Soundararajan, M.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2008-12-21, 公開日: 2009-01-06, 最終更新日: 2023-09-06)

• 主引用文献: Filippakopoulos, P.,Barr, A.,Pike, A.C.W.,Berridge, G.,Elkins, J.,Fedorov, O.,Keates, T.,Savitsky, P.,Soundararajan, M.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.; Crystal Structure of Human Mitogen-Activated Protein Kinase Kinase 6 (MEK6) Activated Mutant (S207D, T211D); To be Published,

実験手法

X-RAY DIFFRACTION (2.26 Å)