3FMD
Crystal Structure of Human Haspin with an Isoquinoline ligand
3FMD の概要
エントリーDOI | 10.2210/pdb3fmd/pdb |
分子名称 | Serine/threonine-protein kinase haspin, N-[2-(4-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINE SULFONAMIDE, NICKEL (II) ION, ... (5 entities in total) |
機能のキーワード | haspin, germ cell associated 2, haploid germ cell specific nuclear protein kinase, atp-binding, cell cycle, chromatin regulator, kinase, magnesium, nucleotide-binding, nucleus, phosphoprotein, serine/threonine-protein kinase, transferase, structural genomics consortium, sgc |
由来する生物種 | Homo sapiens (Human) |
細胞内の位置 | Nucleus : Q8TF76 |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 41278.61 |
構造登録者 | Filippakopoulos, P.,Eswaran, J.,Keates, T.,Burgess-Brown, N.,Fedorov, O.,Pike, A.C.W.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2008-12-21, 公開日: 2008-12-30, 最終更新日: 2023-09-06) |
主引用文献 | Filippakopoulos, P.,Eswaran, J.,Keates, T.,Burgess-Brown, N.,Fedorov, O.,Pike, A.C.W.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S. Crystal Structure of Human Haspin with an Isoquinoline ligand To be Published, |
実験手法 | X-RAY DIFFRACTION (2 Å) |
構造検証レポート
検証レポート(詳細版)をダウンロード