3FKV
AmpC K67R mutant complexed with benzo(b)thiophene-2-boronic acid (bzb)
Summary for 3FKV
Entry DOI | 10.2210/pdb3fkv/pdb |
Related | 1C3B 3FKW |
Descriptor | Beta-lactamase, BENZO[B]THIOPHENE-2-BORONIC ACID, PHOSPHATE ION, ... (5 entities in total) |
Functional Keywords | ampc, k67r, beta-lactamase, general base, antibiotic resistance, periplasm, hydrolase |
Biological source | Escherichia coli |
Cellular location | Periplasm: P00811 |
Total number of polymer chains | 2 |
Total formula weight | 79721.98 |
Authors | Chen, Y.,McReynolds, A.,Shoichet, B.K. (deposition date: 2008-12-17, release date: 2009-03-24, Last modification date: 2023-09-06) |
Primary citation | Chen, Y.,McReynolds, A.,Shoichet, B.K. Re-examining the role of Lys67 in class C beta-lactamase catalysis. Protein Sci., 18:662-669, 2009 Cited by PubMed: 19241376DOI: 10.1002/pro.60 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.847 Å) |
Structure validation
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