3FKO
P38 kinase crystal structure in complex with RO3668
Summary for 3FKO
Entry DOI | 10.2210/pdb3fko/pdb |
Related | 3FI4 3FKL 3FKN |
Descriptor | Mitogen-activated protein kinase 14, 3-(2-chlorophenyl)-6-(2-fluorophenoxy)-2H-indazole (3 entities in total) |
Functional Keywords | p38; map kinase; serine/threonine kinase, atp-binding, kinase, nucleotide-binding, nucleus, phosphoprotein, serine/threonine-protein kinase, transferase, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm (By similarity): Q16539 |
Total number of polymer chains | 1 |
Total formula weight | 43059.47 |
Authors | Kuglstatter, A.,Knapp, M. (deposition date: 2008-12-17, release date: 2009-12-22, Last modification date: 2023-09-06) |
Primary citation | Arora, N.,Williams, C.,Delano, W.,Will, D.,Kuglstatter, A. Mapping Binding Pocket Volume: Potential Applications towards Ligand Design and Selectivity To be Published, |
Experimental method |
Structure validation
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