3FKB
Structure of NDPK H122G and tenofovir-diphosphate
Summary for 3FKB
Entry DOI | 10.2210/pdb3fkb/pdb |
Related | 1b4s 1f3f 2bef |
Descriptor | Nucleoside diphosphate kinase, cytosolic, [(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-phosphonooxy-phosphinic acid, MAGNESIUM ION, ... (7 entities in total) |
Functional Keywords | an hexamer structure, atp-binding, kinase, magnesium, metal-binding, nucleotide metabolism, nucleotide-binding, phosphoprotein, transferase |
Biological source | Dictyostelium discoideum (Slime mold) |
Cellular location | Cytoplasm: P22887 |
Total number of polymer chains | 6 |
Total formula weight | 103334.94 |
Authors | Morera, S.,Chen, Y.X. (deposition date: 2008-12-16, release date: 2009-09-29, Last modification date: 2023-11-01) |
Primary citation | Koch, K.,Chen, Y.X.,Feng, J.Y.,Borroto-Esoda, K.,Deville-Bonne, D.,Gallois-Montbrun, S.,Janin, J.,Morera, S. Nucleoside diphosphate kinase and the activation of antiviral phosphonate analogs of nucleotides: binding mode and phosphorylation of tenofovir derivatives Nucleosides Nucleotides Nucleic Acids, 28:776-792, 2009 Cited by PubMed: 20183617DOI: 10.1080/15257770903155899 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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