3FKB
Structure of NDPK H122G and tenofovir-diphosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Nucleoside diphosphate kinase, cytosolic | polymer | 155 | 16735.2 | 6 | UniProt (P22887) Pfam (PF00334) | Dictyostelium discoideum (Slime mold) | NDP kinase, NDK |
| 2 | G, J, M, T, V (A, B, C, E, F) | [(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-phosphonooxy-phosphinic acid | non-polymer | 367.2 | 5 | Chemie (TNM) | |||
| 3 | H, K, N, Q, U... (A, B, C, D, E...) | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) | |||
| 4 | I, L, S, X, Y (A, B, D, F) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 5 | O, R (C, D) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 6 | P (D) | [2-(6-AMINO-9H-PURIN-9-YL)-1-METHYLETHOXY]METHYL-TRIPHOSPHATE | non-polymer | 447.2 | 1 | Chemie (TNV) | |||
| 7 | AA, BA, CA, DA, EA... (B, C, D, E, F...) | water | water | 18.0 | 1278 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 155 (UniProt: P22887)
| PDB | External Database | Details |
|---|---|---|
| Gly 122 | His 122 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 100411.5 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 2923.5 | |
| All* | Total formula weight | 103334.9 |
