3FKB

Structure of NDPK H122G and tenofovir-diphosphate

Summary for 3FKB

Entry DOI	10.2210/pdb3fkb/pdb
Related	1b4s 1f3f 2bef
Descriptor	Nucleoside diphosphate kinase, cytosolic, [(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-phosphonooxy-phosphinic acid, MAGNESIUM ION, ... (7 entities in total)
Functional Keywords	an hexamer structure, atp-binding, kinase, magnesium, metal-binding, nucleotide metabolism, nucleotide-binding, phosphoprotein, transferase
Biological source	Dictyostelium discoideum (Slime mold)
Cellular location	Cytoplasm: P22887
Total number of polymer chains	6
Total formula weight	103334.94
Authors	Morera, S.,Chen, Y.X. (deposition date: 2008-12-16, release date: 2009-09-29, Last modification date: 2023-11-01)
Primary citation	Koch, K.,Chen, Y.X.,Feng, J.Y.,Borroto-Esoda, K.,Deville-Bonne, D.,Gallois-Montbrun, S.,Janin, J.,Morera, S. Nucleoside diphosphate kinase and the activation of antiviral phosphonate analogs of nucleotides: binding mode and phosphorylation of tenofovir derivatives Nucleosides Nucleotides Nucleic Acids, 28:776-792, 2009 Cited by PubMed: 20183617 DOI: 10.1080/15257770903155899 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation