3FF7

Structure of NK cell receptor KLRG1 bound to E-cadherin

Summary for 3FF7

Entry DOI	10.2210/pdb3ff7/pdb
Related	3FF8 3FF9
Descriptor	Epithelial cadherin, Killer cell lectin-like receptor subfamily G member 1, ACETIC ACID, ... (4 entities in total)
Functional Keywords	klrg1-cadherin complex, calcium, cell adhesion, cell junction, cell membrane, cleavage on pair of basic residues, disease mutation, glycoprotein, membrane, phosphoprotein, polymorphism, transmembrane, alternative splicing, lectin, receptor, signal-anchor, cell adhesion-immune system complex, cell adhesion/immune system
Biological source	Homo sapiens (human) More
Cellular location	Cell junction : P12830 Cell membrane ; Single-pass type II membrane protein : Q96E93
Total number of polymer chains	4
Total formula weight	48254.45
Authors	Li, Y.,Mariuzza, R.A. (deposition date: 2008-12-02, release date: 2009-07-28, Last modification date: 2024-04-03)
Primary citation	Li, Y.,Hofmann, M.,Wang, Q.,Teng, L.,Chlewicki, L.K.,Pircher, H.,Mariuzza, R.A. Structure of natural killer cell receptor KLRG1 bound to E-cadherin reveals basis for MHC-independent missing self recognition. Immunity, 31:35-46, 2009 Cited by PubMed: 19604491 DOI: 10.1016/j.immuni.2009.04.019 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation