3FF7

Structure of NK cell receptor KLRG1 bound to E-cadherin

3FF7 の概要

• エントリーDOI: 10.2210/pdb3ff7/pdb
• 関連するPDBエントリー: 3FF8 3FF9
• 分子名称: Epithelial cadherin, Killer cell lectin-like receptor subfamily G member 1, ACETIC ACID, ... (4 entities in total)
• 機能のキーワード: klrg1-cadherin complex, calcium, cell adhesion, cell junction, cell membrane, cleavage on pair of basic residues, disease mutation, glycoprotein, membrane, phosphoprotein, polymorphism, transmembrane, alternative splicing, lectin, receptor, signal-anchor, cell adhesion-immune system complex, cell adhesion/immune system
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cell junction : P12830; Cell membrane ; Single-pass type II membrane protein : Q96E93
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 48254.45

構造登録者

Li, Y.,Mariuzza, R.A. (登録日: 2008-12-02, 公開日: 2009-07-28, 最終更新日: 2024-04-03)

• 主引用文献: Li, Y.,Hofmann, M.,Wang, Q.,Teng, L.,Chlewicki, L.K.,Pircher, H.,Mariuzza, R.A.; Structure of natural killer cell receptor KLRG1 bound to E-cadherin reveals basis for MHC-independent missing self recognition.; Immunity, 31:35-46, 2009; PubMed: 19604491; DOI: 10.1016/j.immuni.2009.04.019

実験手法

X-RAY DIFFRACTION (1.8 Å)