3FEV

Crystal structure of the chimeric muscarinic toxin MT7 with loop 1 from MT1.

3FEV の概要

• エントリーDOI: 10.2210/pdb3fev/pdb
• 関連するPDBエントリー: 2VLW
• 分子名称: Fusion of Muscarinic toxin 1, Muscarinic m1-toxin1, SULFATE ION (3 entities in total)
• 機能のキーワード: chimera, acetylcholine receptor inhibitor, green mamba snake toxin, hm1 muscarinic receptor, toxin, neurotoxin, muscarinic toxin, postsynaptic neurotoxin, secreted
• 由来する生物種: Dendroaspis angusticeps (eastern green mamba)
• 細胞内の位置: Secreted : Q8QGR0
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 22321.57

構造登録者

Stura, E.A.,Menez, R.,Mourier, G.,Fruchart-Gaillard, C.,Menez, A.,Servant, D. (登録日: 2008-12-01, 公開日: 2009-12-22, 最終更新日: 2023-11-01)

• 主引用文献: Fruchart-Gaillard, C.,Mourier, G.,Blanchet, G.,Vera, L.,Gilles, N.,Menez, R.,Marcon, E.,Stura, E.A.,Servent, D.; Engineering of three-finger fold toxins creates ligands with original pharmacological profiles for muscarinic and adrenergic receptors.; Plos One, 7:e39166-e39166, 2012; PubMed: 22720062; DOI: 10.1371/journal.pone.0039166

実験手法

X-RAY DIFFRACTION (1.3 Å)