3FER

Crystal structure of n-terminal actin-binding domain from human filamin b (tandem ch-domains). northeast structural genomics consortium target hr5571a.

3FER の概要

• エントリーDOI: 10.2210/pdb3fer/pdb
• 分子名称: Filamin-B, ACETIC ACID (3 entities in total)
• 機能のキーワード: x-ray nesg hr5571a actin-binding domain, structural genomics, psi-2, protein structure initiative, northeast structural genomics consortium, actin-binding, alternative splicing, cytoplasm, cytoskeleton, developmental protein, differentiation, disease mutation, dwarfism, myogenesis, phosphoprotein, polymorphism, actin binding protein
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Isoform 1: Cytoplasm, cell cortex. Isoform 2: Cytoplasm, cytoskeleton. Isoform 3: Cytoplasm, cytoskeleton. Isoform 6: Cytoplasm, cytoskeleton: O75369
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 122279.78

構造登録者

Kuzin, A.P.,Abashidze, M.,Seetharaman, R.,Shastry, R.,Sahdev, S.,Ciccosanti, C.,Xiao, R.,Everett, J.K.,Huang, Y.,Acton, T.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F.,Northeast Structural Genomics Consortium (NESG) (登録日: 2008-11-30, 公開日: 2009-01-06, 最終更新日: 2023-11-22)

• 主引用文献: Kuzin, A.P.,Abashidze, M.,Seetharaman, R.,Shastry, R.,Sahdev, S.,Ciccosanti, C.,Xiao, R.,Everett, J.K.,Huang, Y.,Acton, T.,Rost, B.,Montelione, G.T.,Tong, L.,Hunt, J.F.; Crystal structure of n-terminal actin-binding domain from human filamin b (tandem ch-domains). northeast structural genomics consortium target hr5571a.; To be Published,

実験手法

X-RAY DIFFRACTION (2.4 Å)