3FEP

Crystal structure of the R132K:R111L:L121E:R59W-CRABPII mutant complexed with a synthetic ligand (merocyanin) at 2.60 angstrom resolution.

3FEP の概要

• エントリーDOI: 10.2210/pdb3fep/pdb
• 関連するPDBエントリー: 2fr3 2fs6 2g7b 3f8a 3FEK 3FEL 3FEN
• 分子名称: Cellular retinoic acid-binding protein 2, (2E,4E,6E)-3-methyl-6-(1,3,3-trimethyl-1,3-dihydro-2H-indol-2-ylidene)hexa-2,4-dienal, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (4 entities in total)
• 機能のキーワード: merocyanin, crabpii, retinoic acid, retinoid, psb, protonated schiff base, fluorescence, crabp, nucleus, retinol-binding, transport, vitamin a, transport protein
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 16017.33

構造登録者

Jia, X.,Geiger, J.H. (登録日: 2008-11-30, 公開日: 2009-11-10, 最終更新日: 2023-09-06)

• 主引用文献: Yapici, I.,Lee, K.S.,Berbasova, T.,Nosrati, M.,Jia, X.,Vasileiou, C.,Wang, W.,Santos, E.M.,Geiger, J.H.,Borhan, B.; "Turn-on" protein fluorescence: in situ formation of cyanine dyes.; J.Am.Chem.Soc., 137:1073-1080, 2015; PubMed: 25534273; DOI: 10.1021/ja506376j

実験手法

X-RAY DIFFRACTION (2.6 Å)