3FEP
Crystal structure of the R132K:R111L:L121E:R59W-CRABPII mutant complexed with a synthetic ligand (merocyanin) at 2.60 angstrom resolution.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Cellular retinoic acid-binding protein 2 | polymer | 137 | 15554.7 | 1 | UniProt (P29373) Pfam (PF00061) In PDB | Homo sapiens (Human) | Cellular retinoic acid-binding protein II, CRABP-II |
| 2 | A | (2E,4E,6E)-3-methyl-6-(1,3,3-trimethyl-1,3-dihydro-2H-indol-2-ylidene)hexa-2,4-dienal | non-polymer | 267.4 | 1 | Chemie (LMC) | |||
| 3 | A | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 4 | water | water | 18.0 | 39 | Chemie (HOH) |
Sequence modifications
A: 1 - 137 (UniProt: P29373)
| PDB | External Database | Details |
|---|---|---|
| Trp 59 | Arg 60 | engineered mutation |
| Leu 111 | Arg 112 | engineered mutation |
| Glu 121 | Leu 122 | engineered mutation |
| Lys 132 | Arg 133 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15554.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 462.6 | |
| All* | Total formula weight | 16017.3 |
