3FEE

The high resolution structure of human glutamate carboxypeptidase III (GCPIII/NAALADase II) in complex with quisqualic acid

3FEE の概要

• エントリーDOI: 10.2210/pdb3fee/pdb
• 関連するPDBエントリー: 3FEC 3FED 3FF3
• 分子名称: Glutamate carboxypeptidase III, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: metallopeptidase, bimetallic active site, n-glycosylation, calcium cation, chloride anion, zinc ions, carboxypeptidase, dipeptidase, glycoprotein, hydrolase, membrane, metal-binding, metalloprotease, multifunctional enzyme, protease, signal-anchor, transmembrane
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 81424.08

構造登録者

Lubkowski, J.,Barinka, C.,Hlouchova, K. (登録日: 2008-11-28, 公開日: 2009-08-25, 最終更新日: 2023-09-06)

• 主引用文献: Hlouchova, K.,Barinka, C.,Konvalinka, J.,Lubkowski, J.; Structural insight into the evolutionary and pharmacologic homology of glutamate carboxypeptidases II and III; Febs J., 276:4448-4462, 2009; PubMed: 19678840; DOI: 10.1111/j.1742-4658.2009.07152.x

実験手法

X-RAY DIFFRACTION (1.56 Å)