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3FEE

The high resolution structure of human glutamate carboxypeptidase III (GCPIII/NAALADase II) in complex with quisqualic acid

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Glutamate carboxypeptidase IIIpolymer70779940.61UniProt (Q9Y3Q0)
Pfam (PF02225)
Pfam (PF04389)
Pfam (PF04253)
Homo sapiens (human)N-acetylated-alpha-linked acidic dipeptidase 2, N-acetylated-alpha-linked acidic dipeptidase II, NAALADase II
2B
(B)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.41In PDB
GlyTouCan (G42666HT)
3C, D, E
(A)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.23Chemie (NAG)
4F, G
(A)
ZINC IONnon-polymer65.42Chemie (ZN)
5H
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
6I
(A)
CALCIUM IONnon-polymer40.11Chemie (CA)
7J
(A)
(S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACIDnon-polymer189.11Chemie (QUS)
8K
(A)
waterwater18.0828Chemie (HOH)
Sequence modifications
A: 36 - 740 (UniProt: Q9Y3Q0)
PDBExternal DatabaseDetails
Arg 34-expression tag
Ser 35-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight79940.6
BranchedNumber of molecules1
Total formula weight424.4
Non-Polymers*Number of molecules8
Total formula weight1059.1
All*Total formula weight81424.1
*Water molecules are not included.

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PDB entries from 2025-06-11

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