3FED
The high resolution structure of human glutamate carboxypeptidase III (GCPIII/NAALADase II) in complex with a transition state analog of Glu-Glu
Summary for 3FED
Entry DOI | 10.2210/pdb3fed/pdb |
Related | 3FEC 3FEE 3FF3 |
Descriptor | Glutamate carboxypeptidase III, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total) |
Functional Keywords | metallopeptidase, bimetallic active site, n-glycosylation, calcium cation, chloride anion, zinc ions, carboxypeptidase, dipeptidase, glycoprotein, hydrolase, membrane, metal-binding, metalloprotease, multifunctional enzyme, protease, signal-anchor, transmembrane |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 81546.18 |
Authors | Lubkowski, J.,Barinka, C.,Hlouchova, K. (deposition date: 2008-11-28, release date: 2009-08-25, Last modification date: 2023-09-06) |
Primary citation | Hlouchova, K.,Barinka, C.,Konvalinka, J.,Lubkowski, J. Structural insight into the evolutionary and pharmacologic homology of glutamate carboxypeptidases II and III Febs J., 276:4448-4462, 2009 Cited by PubMed: 19678840DOI: 10.1111/j.1742-4658.2009.07152.x PDB entries with the same primary citation |
Experimental method |
Structure validation
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