3FEC

Crystal structure of human Glutamate Carboxypeptidase III (GCPIII/NAALADase II), pseudo-unliganded

Summary for 3FEC

Entry DOI	10.2210/pdb3fec/pdb
Related	3FED 3FEE 3FF3
Descriptor	Glutamate carboxypeptidase III, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ... (10 entities in total)
Functional Keywords	metallopeptidase; bimetallic active site; n-glycosylation; calcium cation; chloride anion; zinc ions;, carboxypeptidase, dipeptidase, glycoprotein, hydrolase, membrane, metal-binding, metalloprotease, multifunctional enzyme, protease, signal-anchor, transmembrane
Biological source	Homo sapiens (man)
Total number of polymer chains	1
Total formula weight	81775.53
Authors	Barinka, C.,Lubkowski, J.,Hlouchova, K. (deposition date: 2008-11-28, release date: 2009-08-25, Last modification date: 2023-09-06)
Primary citation	Hlouchova, K.,Barinka, C.,Konvalinka, J.,Lubkowski, J. Structural insight into the evolutionary and pharmacologic homology of glutamate carboxypeptidases II and III Febs J., 276:4448-4462, 2009 Cited by PubMed: 19678840 DOI: 10.1111/j.1742-4658.2009.07152.x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.49 Å)

Structure validation