3FDM
alpha/beta foldamer in complex with Bcl-xL
Summary for 3FDM
Entry DOI | 10.2210/pdb3fdm/pdb |
Related | 3FDL |
Descriptor | Apoptosis regulator Bcl-X, alpha/beta-peptide foldamer, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | protein-peptide complex, helical bundle, foldamer, apoptosis, alternative splicing, membrane, mitochondrion, nucleus, transmembrane |
Biological source | Homo sapiens (Human) More |
Cellular location | Isoform Bcl-X(L): Mitochondrion inner membrane : Q07817 |
Total number of polymer chains | 6 |
Total formula weight | 59677.92 |
Authors | Fairlie, W.D.,Lee, E.F.,Smith, B.J.,Czabotar, P.E.,Colman, P.M.,Sadowsky, J.D.,Peterson-Kaufman, K.J.,Gellman, S.H. (deposition date: 2008-11-26, release date: 2009-03-10, Last modification date: 2023-11-15) |
Primary citation | Lee, E.F.,Sadowsky, J.D.,Smith, B.J.,Czabotar, P.E.,Peterson-Kaufman, K.J.,Colman, P.M.,Gellman, S.H.,Fairlie, W.D. High-Resolution Structural Characterization of a Helical alpha/beta-Peptide Foldamer Bound to the Anti-Apoptotic Protein Bcl-x(L) Angew.Chem.Int.Ed.Engl., 48:4318-4322, 2009 Cited by PubMed: 19229915DOI: 10.1002/anie.200805761 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.26 Å) |
Structure validation
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