Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0042981 | biological_process | regulation of apoptotic process |
| B | 0042981 | biological_process | regulation of apoptotic process |
| C | 0042981 | biological_process | regulation of apoptotic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 210 |
| Chain | Residue |
| A | GLU92 |
| A | ALA93 |
| A | GLU96 |
| A | TYR195 |
| A | ASN198 |
| A | EDO213 |
| D | ARG15 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 211 |
| Chain | Residue |
| A | THR172 |
| B | ALA168 |
| B | TRP169 |
| B | THR172 |
| B | HOH238 |
| A | ALA168 |
| A | TRP169 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 212 |
| Chain | Residue |
| A | ASP156 |
| B | LYS20 |
| B | TYR22 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 213 |
| Chain | Residue |
| A | GLU96 |
| A | ARG100 |
| A | ASN198 |
| A | EDO210 |
| A | HOH258 |
| D | ARG15 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 214 |
| Chain | Residue |
| A | ASP95 |
| A | GLU98 |
| A | LEU99 |
| A | HOH284 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 215 |
| Chain | Residue |
| A | ARG102 |
| A | PHE105 |
| A | SER145 |
| A | PHE146 |
| A | ALA149 |
| A | HOH264 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 216 |
| Chain | Residue |
| A | HOH35 |
| A | GLN88 |
| A | ASP95 |
| A | HOH249 |
| A | HOH251 |
| B | TYR15 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 210 |
| Chain | Residue |
| B | LEU194 |
| B | TYR195 |
| B | GLY196 |
| B | HOH242 |
| B | HOH290 |
| E | ARG15 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 211 |
| Chain | Residue |
| B | SER18 |
| B | TYR22 |
| B | SER23 |
| B | HOH30 |
| B | ASN197 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 212 |
| Chain | Residue |
| A | SER0 |
| A | VAL163 |
| B | SER23 |
| B | TRP24 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 213 |
| Chain | Residue |
| A | TRP24 |
| B | SER2 |
| B | HOH76 |
| B | SER164 |
Functional Information from PROSITE/UniProt
| site_id | PS01080 |
| Number of Residues | 19 |
| Details | BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. LFrDGv.NWGRIVAFFsFGG |
| Chain | Residue | Details |
| A | LEU130-GLY148 | |
| site_id | PS01258 |
| Number of Residues | 12 |
| Details | BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WIqenGGWDtFV |
| Chain | Residue | Details |
| A | TRP181-VAL192 | |
| site_id | PS01259 |
| Number of Residues | 15 |
| Details | BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. VkqaLReAGDEFELR |
| Chain | Residue | Details |
| A | VAL86-ARG100 | |
| site_id | PS01260 |
| Number of Residues | 21 |
| Details | BH4_1 Apoptosis regulator, Bcl-2 family BH4 motif signature. SNRELVvDFLSYKLSQKGYsW |
| Chain | Residue | Details |
| A | SER4-TRP24 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | SITE: Cleavage; by caspase-1 |
| Chain | Residue | Details |
| A | GLY117 | |
| B | GLY117 | |
| C | GLY117 | |
| Chain | Residue | Details |
| A | PHE105 | |
| B | PHE105 | |
| C | PHE105 | |
| Chain | Residue | Details |
| A | THR118 | |
| B | THR118 | |
| C | THR118 | |
