3FDE
Mouse UHRF1 SRA domain bound with hemi-methylated CpG DNA, crystal structure in space group C222(1) at 1.4 A resolution
Summary for 3FDE
Entry DOI | 10.2210/pdb3fde/pdb |
Related | 2ZO0 2ZO1 2ZO2 3F8I 3F8J |
Descriptor | E3 ubiquitin-protein ligase UHRF1, 5'-D(*CP*CP*AP*TP*GP*(5CM)P*GP*CP*TP*GP*AP*C)-3', 5'-D(*GP*TP*CP*AP*GP*CP*GP*CP*AP*TP*GP*G)-3', ... (7 entities in total) |
Functional Keywords | sra domain, base flipping, dna cpg methylation, cell cycle, developmental protein, dna damage, dna repair, dna-binding, ligase, metal-binding, nucleus, phosphoprotein, transcription, transcription regulation, ubl conjugation, ubl conjugation pathway, zinc, zinc-finger |
Biological source | Mus musculus More |
Cellular location | Nucleus: Q8VDF2 |
Total number of polymer chains | 6 |
Total formula weight | 63970.50 |
Authors | Hashimoto, H.,Horton, J.R.,Zhang, X.,Cheng, X. (deposition date: 2008-11-25, release date: 2009-01-06, Last modification date: 2023-12-27) |
Primary citation | Hashimoto, H.,Horton, J.R.,Zhang, X.,Cheng, X. UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications. Epigenetics, 4:8-14, 2009 Cited by PubMed: 19077538PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.41 Å) |
Structure validation
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