3F9Z
Structural Insights into Lysine Multiple Methylation by SET Domain Methyltransferases, SET8-Y245F / H4-Lys20 / AdoHcy
Summary for 3F9Z
Entry DOI | 10.2210/pdb3f9z/pdb |
Related | 1ZKK 3F9W 3F9X 3F9Y |
Descriptor | Histone-lysine N-methyltransferase SETD8, Histone H4, S-ADENOSYL-L-HOMOCYSTEINE, ... (4 entities in total) |
Functional Keywords | methyltransferase, histone, set, lysine, alternative splicing, cell cycle, cell division, chromatin regulator, chromosomal protein, coiled coil, mitosis, nucleus, repressor, s-adenosyl-l-methionine, transcription, transcription regulation, acetylation, dna-binding, methylation, nucleosome core, transferase |
Biological source | Homo sapiens More |
Cellular location | Nucleus: Q9NQR1 P62805 |
Total number of polymer chains | 8 |
Total formula weight | 81772.90 |
Authors | Couture, J.-F.,Dirk, L.M.A.,Brunzelle, J.S.,Houtz, R.L.,Trievel, R.C. (deposition date: 2008-11-14, release date: 2008-11-25, Last modification date: 2023-09-06) |
Primary citation | Couture, J.F.,Dirk, L.M.,Brunzelle, J.S.,Houtz, R.L.,Trievel, R.C. Structural origins for the product specificity of SET domain protein methyltransferases. Proc.Natl.Acad.Sci.Usa, 105:20659-20664, 2008 Cited by PubMed: 19088188DOI: 10.1073/pnas.0806712105 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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