3F9Z

Structural Insights into Lysine Multiple Methylation by SET Domain Methyltransferases, SET8-Y245F / H4-Lys20 / AdoHcy

3F9Z の概要

• エントリーDOI: 10.2210/pdb3f9z/pdb
• 関連するPDBエントリー: 1ZKK 3F9W 3F9X 3F9Y
• 分子名称: Histone-lysine N-methyltransferase SETD8, Histone H4, S-ADENOSYL-L-HOMOCYSTEINE, ... (4 entities in total)
• 機能のキーワード: methyltransferase, histone, set, lysine, alternative splicing, cell cycle, cell division, chromatin regulator, chromosomal protein, coiled coil, mitosis, nucleus, repressor, s-adenosyl-l-methionine, transcription, transcription regulation, acetylation, dna-binding, methylation, nucleosome core, transferase
• 由来する生物種: Homo sapiens; 詳細
• 細胞内の位置: Nucleus: Q9NQR1 P62805
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 81772.90

構造登録者

Couture, J.-F.,Dirk, L.M.A.,Brunzelle, J.S.,Houtz, R.L.,Trievel, R.C. (登録日: 2008-11-14, 公開日: 2008-11-25, 最終更新日: 2023-09-06)

• 主引用文献: Couture, J.F.,Dirk, L.M.,Brunzelle, J.S.,Houtz, R.L.,Trievel, R.C.; Structural origins for the product specificity of SET domain protein methyltransferases.; Proc.Natl.Acad.Sci.Usa, 105:20659-20664, 2008; PubMed: 19088188; DOI: 10.1073/pnas.0806712105

実験手法

X-RAY DIFFRACTION (1.6 Å)