3F9M
Human pancreatic glucokinase in complex with glucose and activator showing a mobile flap
Summary for 3F9M
Entry DOI | 10.2210/pdb3f9m/pdb |
Related | 1V4S 1V4T |
Descriptor | Glucokinase, alpha-D-glucopyranose, 2-AMINO-4-FLUORO-5-[(1-METHYL-1H-IMIDAZOL-2-YL)SULFANYL]-N-(1,3-THIAZOL-2-YL)BENZAMIDE, ... (4 entities in total) |
Functional Keywords | glucokinase, hexokinase iv, atp-binding, diabetes mellitus, disease mutation, glycolysis, kinase, nucleotide-binding, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 53525.75 |
Authors | Petit, P.,Gluais, L.,Lagarde, A.,Vuillard, L.,Boutin, J.A.,Ferry, G. (deposition date: 2008-11-14, release date: 2008-12-02, Last modification date: 2023-11-01) |
Primary citation | Petit, P.,Antoine, M.,Ferry, G.,Boutin, J.A.,Lagarde, A.,Gluais, L.,Vincentelli, R.,Vuillard, L. The active conformation of human glucokinase is not altered by allosteric activators Acta Crystallogr.,Sect.D, 67:929-935, 2011 Cited by PubMed: 22101819DOI: 10.1107/S0907444911036729 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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