3F9M

Human pancreatic glucokinase in complex with glucose and activator showing a mobile flap

3F9M の概要

• エントリーDOI: 10.2210/pdb3f9m/pdb
• 関連するPDBエントリー: 1V4S 1V4T
• 分子名称: Glucokinase, alpha-D-glucopyranose, 2-AMINO-4-FLUORO-5-[(1-METHYL-1H-IMIDAZOL-2-YL)SULFANYL]-N-(1,3-THIAZOL-2-YL)BENZAMIDE, ... (4 entities in total)
• 機能のキーワード: glucokinase, hexokinase iv, atp-binding, diabetes mellitus, disease mutation, glycolysis, kinase, nucleotide-binding, transferase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 53525.75

構造登録者

Petit, P.,Gluais, L.,Lagarde, A.,Vuillard, L.,Boutin, J.A.,Ferry, G. (登録日: 2008-11-14, 公開日: 2008-12-02, 最終更新日: 2023-11-01)

• 主引用文献: Petit, P.,Antoine, M.,Ferry, G.,Boutin, J.A.,Lagarde, A.,Gluais, L.,Vincentelli, R.,Vuillard, L.; The active conformation of human glucokinase is not altered by allosteric activators; Acta Crystallogr.,Sect.D, 67:929-935, 2011; PubMed: 22101819; DOI: 10.1107/S0907444911036729

実験手法

X-RAY DIFFRACTION (1.5 Å)