3F8A

Crystal Structure of the R132K:R111L:L121E:R59W Mutant of Cellular Retinoic Acid-Binding Protein Type II Complexed with C15-aldehyde (a retinal analog) at 1.95 Angstrom resolution.

3F8A の概要

• エントリーDOI: 10.2210/pdb3f8a/pdb
• 関連するPDBエントリー: 3CR6 3F9D 3FA6 3FA7 3FA8 3FA9
• 分子名称: Cellular retinoic acid-binding protein 2, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 1,3,3-trimethyl-2-[(1E,3E)-3-methylpenta-1,3-dien-1-yl]cyclohexene, ... (4 entities in total)
• 機能のキーワード: crabpii, retinal, protonated schiff base, c15-aldehyde, retinoic acid, retinoid, nucleus, retinol-binding, transport, vitamin a, transport protein
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Cytoplasm: P29373
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 16041.41

構造登録者

Jia, X.,Geiger, J.H. (登録日: 2008-11-12, 公開日: 2009-11-10, 最終更新日: 2023-09-06)

• 主引用文献: Lee, K.S.,Berbasova, T.,Vasileiou, C.,Jia, X.,Wang, W.,Choi, Y.,Nossoni, F.,Geiger, J.H.,Borhan, B.; Probing Wavelength Regulation with an Engineered Rhodopsin Mimic and a C15-Retinal Analogue; Chempluschem, 77:273-276, 2012

実験手法

X-RAY DIFFRACTION (1.95 Å)