3F7Q
First pair of Fibronectin type III domains and part of the connecting segment of the integrin beta4
Summary for 3F7Q
Entry DOI | 10.2210/pdb3f7q/pdb |
Related | 1QG3 3F7P 3F7R |
Descriptor | Integrin beta-4, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... (7 entities in total) |
Functional Keywords | integrin, hemidesmosome, cell adhesion, carcinoma, epidermolysis bullosa, alternative splicing, disease mutation, glycoprotein, membrane, phosphoprotein, polymorphism, receptor, transmembrane |
Biological source | Homo sapiens (Human) |
Cellular location | Membrane; Single-pass type I membrane protein: P16144 |
Total number of polymer chains | 2 |
Total formula weight | 53030.55 |
Authors | de Pereda, J.M. (deposition date: 2008-11-10, release date: 2009-03-10, Last modification date: 2023-11-01) |
Primary citation | de Pereda, J.M.,Lillo, M.P.,Sonnenberg, A. Structural basis of the interaction between integrin alpha6beta4 and plectin at the hemidesmosomes Embo J., 28:1180-1190, 2009 Cited by PubMed: 19242489DOI: 10.1038/emboj.2009.48 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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