3F6Y
Conformational Closure of the Catalytic Site of Human CD38 Induced by Calcium
Summary for 3F6Y
Entry DOI | 10.2210/pdb3f6y/pdb |
Descriptor | ADP-ribosyl cyclase 1, CALCIUM ION (3 entities in total) |
Functional Keywords | calcium loaded structure, active site closure, inhibitory conformation, alternative splicing, diabetes mellitus, glycoprotein, hydrolase, membrane, nad, polymorphism, receptor, signal-anchor, transmembrane |
Biological source | Homo sapiens (Human) |
Cellular location | Membrane; Single-pass type II membrane protein: P28907 |
Total number of polymer chains | 1 |
Total formula weight | 30490.61 |
Authors | Liu, Q.,Graeff, R.,Kriksunov, I.A.,Lam, C.M.C.,Lee, H.C.,Hao, Q. (deposition date: 2008-11-07, release date: 2008-11-18, Last modification date: 2023-11-01) |
Primary citation | Liu, Q.,Graeff, R.,Kriksunov, I.A.,Lam, C.M.C.,Lee, H.C.,Hao, Q. Conformational Closure of the Catalytic Site of Human CD38 Induced by Calcium Biochemistry, 47:13966-13973, 2008 Cited by PubMed: 19117080DOI: 10.1021/bi801642q PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
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