3EYA

Structural basis for membrane binding and catalytic activation of the peripheral membrane enzyme pyruvate oxidase from Escherichia coli

Summary for 3EYA

Entry DOI	10.2210/pdb3eya/pdb
Related	1POW 3EY9
Descriptor	Pyruvate dehydrogenase [cytochrome], THIAMINE DIPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, ... (6 entities in total)
Functional Keywords	pyruvate oxidase, membrane-associated flavoprotein dehydrogenase, interactions with lipids cell membrane, fad, flavoprotein, lipid-binding, magnesium, membrane, oxidoreductase, thiamine pyrophosphate
Biological source	Escherichia coli
Cellular location	Cell membrane; Peripheral membrane protein: P07003
Total number of polymer chains	12
Total formula weight	731702.48
Authors	Neumann, P.,Weidner, A.,Pech, A.,Stubbs, M.T.,Tittmann, K. (deposition date: 2008-10-20, release date: 2008-11-04, Last modification date: 2023-11-01)
Primary citation	Neumann, P.,Weidner, A.,Pech, A.,Stubbs, M.T.,Tittmann, K. Structural basis for membrane binding and catalytic activation of the peripheral membrane enzyme pyruvate oxidase from Escherichia coli. Proc.Natl.Acad.Sci.USA, 105:17390-17395, 2008 Cited by PubMed: 18988747 DOI: 10.1073/pnas.0805027105 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation