3EY6

Crystal structure of the FK506-binding domain of human FKBP38

Summary for 3EY6

Entry DOI	10.2210/pdb3ey6/pdb
Related	2AWG 2F2D
Descriptor	FK506-binding protein 8 (2 entities in total)
Functional Keywords	beta half-barrel, ppiase, immunophilin, apoptosis, host-virus interaction, isomerase, membrane, mitochondrion, phosphoprotein, rotamase, tpr repeat, transmembrane
Biological source	Homo sapiens (human)
Cellular location	Mitochondrion . Isoform 1: Mitochondrion membrane ; Single-pass membrane protein; Cytoplasmic side . Isoform 3: Mitochondrion membrane ; Single-pass membrane protein; Cytoplasmic side : Q14318
Total number of polymer chains	1
Total formula weight	13067.96
Authors	Parthier, C.,Maestre-Martinez, M.,Neumann, P.,Edlich, F.,Fischer, G.,Luecke, C.,Stubbs, M.T. (deposition date: 2008-10-19, release date: 2009-10-27, Last modification date: 2023-09-06)
Primary citation	Maestre-Martinez, M.,Haupt, K.,Edlich, F.,Neumann, P.,Parthier, C.,Stubbs, M.T.,Fischer, G.,Luecke, C. A charge-sensitive loop in the FKBP38 catalytic domain modulates Bcl-2 binding. J.Mol.Recognit., 24:23-34, 2011 Cited by PubMed: 20140889 DOI: 10.1002/jmr.1020 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.05 Å)

Structure validation