3EWP

complex of substrate ADP-ribose with IBV Nsp3 ADRP domain

Summary for 3EWP

• Entry DOI: 10.2210/pdb3ewp/pdb
• Related: 3EWO 3EWQ 3EWR
• Descriptor: Non-structural protein 3, ADENOSINE-5-DIPHOSPHORIBOSE (3 entities in total)
• Functional Keywords: globular like, cytoplasm, hydrolase, membrane, metal-binding, protease, ribosomal frameshifting, rna-binding, thiol protease, transmembrane, zinc, zinc-finger
• Biological source: Avian infectious bronchitis virus (IBV)
• Cellular location: Non-structural protein 3: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 4: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 6: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 7: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 8: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 9: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 10: Host cytoplasm, host perinuclear region (By similarity): P0C6V5
• Total number of polymer chains: 2
• Total formula weight: 39527.21

Authors

Xu, Y.,Cong, L.,Chen, C.,Wei, L.,Zhao, Q.,Xu, X.,Ma, Y.,Bartlam, M.,Rao, Z. (deposition date: 2008-10-16, release date: 2009-01-13, Last modification date: 2023-12-27)

• Primary citation: Xu, Y.,Cong, L.,Chen, C.,Wei, L.,Zhao, Q.,Xu, X.,Ma, Y.,Bartlam, M.,Rao, Z.; Crystal structures of two coronavirus ADP-ribose-1''-monophosphatases and their complexes with ADP-Ribose: a systematic structural analysis of the viral ADRP domain.; J.Virol., 83:1083-1092, 2009; PubMed: 18987156; DOI: 10.1128/JVI.01862-08

Experimental method

X-RAY DIFFRACTION (2 Å)