3EVI

Crystal structure of the thioredoxin-fold domain of human phosducin-like protein 2

3EVI の概要

• エントリーDOI: 10.2210/pdb3evi/pdb
• 分子名称: Phosducin-like protein 2, DI(HYDROXYETHYL)ETHER, SODIUM ION, ... (4 entities in total)
• 機能のキーワード: alpha beta, 3-layer(aba) sandwich, unknown function
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 27271.36

構造登録者

Lou, X.,Bao, R.,Zhou, C.,Chen, Y. (登録日: 2008-10-13, 公開日: 2009-03-03, 最終更新日: 2023-11-01)

主引用文献

Lou, X.,Bao, R.,Zhou, C.Z.,Chen, Y.
Structure of the thioredoxin-fold domain of human phosducin-like protein 2
Acta Crystallogr.,Sect.F, 65:67-70, 2009

PubMed Abstract: Human phosducin-like protein 2 (hPDCL2) has been identified as belonging to subgroup II of the phosducin (Pdc) family. The members of this family share an N-terminal helix domain and a C-terminal thioredoxin-fold (Trx-fold) domain. The X-ray crystal structure of the Trx-fold domain of hPDCL2 was solved at 2.70 A resolution and resembled the Trx-fold domain of rat phosducin. Comparative structural analysis revealed the structural basis of their putative functional divergence.

PubMed: 19193988
DOI: 10.1107/S1744309108037342

実験手法

X-RAY DIFFRACTION (2.7 Å)