3ESL

Crystal structure of the conserved N-terminal domain of the mitotic checkpoint component BUB1

3ESL の概要

• エントリーDOI: 10.2210/pdb3esl/pdb
• 分子名称: Checkpoint serine/threonine-protein kinase BUB1, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID (3 entities in total)
• 機能のキーワード: bub1, mitotic spindle checkpoint, tpr motif, all-alpha domain, mad3-like domain, chromosome instability, atp-binding, cell cycle, kinase, nucleotide-binding, nucleus, phosphorylation, serine/threonine-protein kinase, transferase, kinetochore localization, phosphoprotein
• 由来する生物種: Saccharomyces cerevisiae (brewer's yeast,lager beer yeast,yeast)
• 細胞内の位置: Nucleus: P41695
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 49177.80

構造登録者

Bolanos-Garcia, V.M.,Chirgadze, D.Y.,Blundell, T.L. (登録日: 2008-10-06, 公開日: 2009-02-17, 最終更新日: 2023-12-27)

• 主引用文献: Bolanos-Garcia, V.M.,Kiyomitsu, T.,D'Arcy, S.,Chirgadze, D.Y.,Grossmann, J.G.,Matak-Vinkovic, D.,Venkitaraman, A.R.,Yanagida, M.,Robinson, C.V.,Blundell, T.L.; The Crystal Structure of the N-Terminal Region of BUB1 Provides Insight into the Mechanism of BUB1 Recruitment to Kinetochores.; Structure, 17:105-116, 2009; PubMed: 19141287; DOI: 10.1016/j.str.2008.10.015

実験手法

X-RAY DIFFRACTION (1.74 Å)