3EQ1
The Crystal Structure of Human Porphobilinogen Deaminase at 2.8A resolution
Summary for 3EQ1
Entry DOI | 10.2210/pdb3eq1/pdb |
Descriptor | Porphobilinogen deaminase, 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, SULFATE ION (3 entities in total) |
Functional Keywords | alpha and beta protein, alternative splicing, cytoplasm, disease mutation, heme biosynthesis, porphyrin biosynthesis, transferase |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm (Probable): P08397 |
Total number of polymer chains | 2 |
Total formula weight | 80221.16 |
Authors | Kolstoe, S.E.,Gill, R.,Mohammed, F.,Wood, S.P. (deposition date: 2008-09-30, release date: 2009-03-03, Last modification date: 2023-11-01) |
Primary citation | Gill, R.,Kolstoe, S.E.,Mohammed, F.,Al D-Bass, A.,Mosely, J.E.,Sarwar, M.,Cooper, J.B.,Wood, S.P.,Shoolingin-Jordan, P.M. Structure of human porphobilinogen deaminase at 2.8 A: the molecular basis of acute intermittent porphyria Biochem.J., 420:17-25, 2009 Cited by PubMed: 19207107DOI: 10.1042/BJ20082077 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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