Summary for 3EQ1
| Descriptor | Porphobilinogen deaminase, 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, SULFATE ION (3 entities in total) |
|---|---|
| Functional Keywords | alpha and beta protein, alternative splicing, cytoplasm, disease mutation, heme biosynthesis, porphyrin biosynthesis, transferase |
| Biological source | Homo sapiens (Human) |
| Cellular location | Cytoplasm (Probable) P08397 |
| Total number of polymer chains | 2 |
| Total molecular weight | 80221.16 |
| Authors | Kolstoe, S.E.,Gill, R.,Mohammed, F.,Wood, S.P. (deposition date: 2008-09-30, release date: 2009-03-03, Last modification date: 2011-07-13) |
| Primary citation | Gill, R.,Kolstoe, S.E.,Mohammed, F.,Al D-Bass, A.,Mosely, J.E.,Sarwar, M.,Cooper, J.B.,Wood, S.P.,Shoolingin-Jordan, P.M. Structure of human porphobilinogen deaminase at 2.8 A: the molecular basis of acute intermittent porphyria Biochem.J., 420:17-25, 2009 PubMed: 19207107 (PDB entries with the same primary citation) DOI: 10.1042/BJ20082077  Import into Mendeley |
| Experimental method | X-RAY DIFFRACTION (2.8 Å) |
