3ELP

Structure of cystationine gamma lyase

Summary for 3ELP

Entry DOI	10.2210/pdb3elp/pdb
Descriptor	Cystathionine gamma-lyase (2 entities in total)
Functional Keywords	alpha beta protein, alternative splicing, amino-acid biosynthesis, cysteine biosynthesis, cytoplasm, disease mutation, lyase, phosphoprotein, polymorphism, pyridoxal phosphate
Biological source	Homo sapiens (Human)
Cellular location	Cytoplasm: P32929
Total number of polymer chains	4
Total formula weight	180013.26
Authors	Sun, Q.,Sivaraman, J. (deposition date: 2008-09-23, release date: 2008-11-18, Last modification date: 2023-11-01)
Primary citation	Sun, Q.,Collins, R.,Huang, S.,Holmberg-Schiavone, L.,Anand, G.S.,Tan, C.H.,van-den-Berg, S.,Deng, L.-W.,Moore, P.K.,Karlberg, T.,Sivaraman, J. Structural basis for the inhibition mechanism of human cystathionine gamma-lyase, an enzyme responsible for the production of H(2)S J.Biol.Chem., 284:3076-3085, 2009 Cited by PubMed: 19019829 DOI: 10.1074/jbc.M805459200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation