3ELA

Crystal structure of active site inhibited coagulation factor VIIA mutant in complex with soluble tissue factor

3ELA の概要

• エントリーDOI: 10.2210/pdb3ela/pdb
• 関連するBIRD辞書のPRD_ID: PRD_000369
• 分子名称: Coagulation factor VIIA light chain, Coagulation factor VIIA heavy chain, Tissue factor, ... (8 entities in total)
• 機能のキーワード: serine protease, blood clotting, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 69653.77

構造登録者

Bjelke, J.R.,Fodje, M.,Svensson, L.A. (登録日: 2008-09-21, 公開日: 2008-11-04, 最終更新日: 2023-11-01)

• 主引用文献: Bjelke, J.R.,Olsen, O.H.,Fodje, M.,Svensson, L.A.,Bang, S.,Bolt, G.,Kragelund, B.B.,Persson, E.; Mechanism of the Ca2+-induced enhancement of the intrinsic factor VIIa activity; J.Biol.Chem., 283:25863-25870, 2008; PubMed: 18640965; DOI: 10.1074/jbc.M800841200

実験手法

X-RAY DIFFRACTION (2.2 Å)