3EJJ

Structure of M-CSF bound to the first three domains of FMS

3EJJ の概要

• エントリーDOI: 10.2210/pdb3ejj/pdb
• 分子名称: Colony stimulating factor-1, Macrophage colony-stimulating factor 1 receptor, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: growth factor-receptor complex, receptor tyrosine kinase, cytokine, 4-helix bundle, atp-binding, glycoprotein, immunoglobulin domain, kinase, membrane, nucleotide-binding, phosphoprotein, proto-oncogene, receptor, transferase, transmembrane, tyrosine-protein kinase, cytokine-signaling protein complex, cytokine/signaling protein
• 由来する生物種: Mus musculus (mouse); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 69289.66

構造登録者

Chen, X.,Liu, H.,Focia, P.J.,Shim, A.,He, X. (登録日: 2008-09-18, 公開日: 2008-12-09, 最終更新日: 2023-08-30)

• 主引用文献: Chen, X.,Liu, H.,Focia, P.J.,Shim, A.H.,He, X.; Structure of macrophage colony stimulating factor bound to FMS: diverse signaling assemblies of class III receptor tyrosine kinases.; Proc.Natl.Acad.Sci.USA, 105:18267-18272, 2008; PubMed: 19017797; DOI: 10.1073/pnas.0807762105

実験手法

X-RAY DIFFRACTION (2.4 Å)