3EGU
Crystal structure of the N114A mutant of ABL-SH3 domain
Summary for 3EGU
Entry DOI | 10.2210/pdb3egu/pdb |
Related | 1bbz 2o88 3EG0 3EG1 3EG2 3EG3 |
Descriptor | Proto-oncogene tyrosine-protein kinase ABL1, SULFATE ION, GLYCEROL, ... (4 entities in total) |
Functional Keywords | beta, atp-binding, cell adhesion, cytoskeleton, kinase, lipoprotein, magnesium, manganese, metal-binding, myristate, nucleotide-binding, nucleus, phosphoprotein, proto-oncogene, sh2 domain, sh3 domain, transferase, tyrosine-protein kinase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cytoskeleton. Isoform IB: Nucleus membrane; Lipid-anchor: P00519 |
Total number of polymer chains | 1 |
Total formula weight | 7154.83 |
Authors | Camara-Artigas, A. (deposition date: 2008-09-11, release date: 2009-09-15, Last modification date: 2024-02-21) |
Primary citation | Palencia, A.,Camara-Artigas, A.,Pisabarro, M.T.,Martinez, J.C.,Luque, I. Role of interfacial water molecules in proline-rich ligand recognition by the Src homology 3 domain of Abl. J.Biol.Chem., 285:2823-2833, 2010 Cited by PubMed: 19906645DOI: 10.1074/jbc.M109.048033 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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