3EGU
Crystal structure of the N114A mutant of ABL-SH3 domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Proto-oncogene tyrosine-protein kinase ABL1 | polymer | 63 | 6966.7 | 1 | UniProt (P00519) Pfam (PF00018) In PDB | Homo sapiens (human) | p150, c- ABL, Abelson murine leukemia viral oncogene homolog 1 |
| 2 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | water | water | 18.0 | 19 | Chemie (HOH) |
Sequence modifications
A: 60 - 121 (UniProt: P00519)
| PDB | External Database | Details |
|---|---|---|
| Met 59 | - | initiating methionine |
| Ala 114 | Asn 114 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 6966.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 188.2 | |
| All* | Total formula weight | 7154.8 |
