3EGD
Crystal structure of the mammalian COPII-coat protein Sec23a/24a complexed with the SNARE protein Sec22 and bound to the transport signal sequence of vesicular stomatitis virus glycoprotein
Summary for 3EGD
Entry DOI | 10.2210/pdb3egd/pdb |
Related | 3EFO 3EG9 |
Descriptor | Protein transport protein Sec23A, Protein transport protein Sec24A, Vesicle-trafficking protein SEC22b, ... (6 entities in total) |
Functional Keywords | copii coat, transport signal sequence, vesicle, disease mutation, endoplasmic reticulum, er-golgi transport, golgi apparatus, membrane, protein transport, transport, phosphoprotein, transmembrane |
Biological source | Homo sapiens (Human) More |
Cellular location | Smooth endoplasmic reticulum membrane; Peripheral membrane protein: Q15436 Cytoplasm (By similarity): O95486 Endoplasmic reticulum membrane; Single-pass type IV membrane protein (By similarity): O75396 |
Total number of polymer chains | 4 |
Total formula weight | 189961.13 |
Authors | Goldberg, J.,Mancias, J.D. (deposition date: 2008-09-10, release date: 2008-10-21, Last modification date: 2024-02-21) |
Primary citation | Mancias, J.D.,Goldberg, J. Structural basis of cargo membrane protein discrimination by the human COPII coat machinery. Embo J., 27:2918-2928, 2008 Cited by PubMed: 18843296DOI: 10.1038/emboj.2008.208 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
Download full validation report