3EGD

Crystal structure of the mammalian COPII-coat protein Sec23a/24a complexed with the SNARE protein Sec22 and bound to the transport signal sequence of vesicular stomatitis virus glycoprotein

3EGD の概要

• エントリーDOI: 10.2210/pdb3egd/pdb
• 関連するPDBエントリー: 3EFO 3EG9
• 分子名称: Protein transport protein Sec23A, Protein transport protein Sec24A, Vesicle-trafficking protein SEC22b, ... (6 entities in total)
• 機能のキーワード: copii coat, transport signal sequence, vesicle, disease mutation, endoplasmic reticulum, er-golgi transport, golgi apparatus, membrane, protein transport, transport, phosphoprotein, transmembrane
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Smooth endoplasmic reticulum membrane; Peripheral membrane protein: Q15436; Cytoplasm (By similarity): O95486; Endoplasmic reticulum membrane; Single-pass type IV membrane protein (By similarity): O75396
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 189961.13

構造登録者

Goldberg, J.,Mancias, J.D. (登録日: 2008-09-10, 公開日: 2008-10-21, 最終更新日: 2024-02-21)

• 主引用文献: Mancias, J.D.,Goldberg, J.; Structural basis of cargo membrane protein discrimination by the human COPII coat machinery.; Embo J., 27:2918-2928, 2008; PubMed: 18843296; DOI: 10.1038/emboj.2008.208

実験手法

X-RAY DIFFRACTION (2.7 Å)